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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG
9 ] \ H! I; A2 ]$ Y* y# e* B; |如果是中国长大的,英语能到这种程度真是很不简单。, h, t' U" f) m6 F! Q: \; ?4 u
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http://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html
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FROM LAI JIANG, Department of Chemistry, University of Pennsylvania
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It is a shame to see Nature — which nearly all scientists, including myself
8 \0 v6 V- ]- a. U) z/ X, regard as one of the most prestigious and influential physical-science: U" P2 s1 U9 \# ?+ S
magazines — publish a thinly veiled biased article like this. Granted, this
4 c8 j( v. x3 ]+ `7 lis not a peer-reviewed scientific article and did not go through the' h6 o4 X: u$ l8 `; v/ |. k0 C
scrutiny of picking referees. But to serve as a channel for the general
( t8 `- {; Q; f, V, G4 {' Lpopulace to be in touch with and appreciate science, the authors and editors# _/ g* }6 m; L, M: l4 G
should at least present the readers with facts within the proper context,! l# A0 u: J/ B2 ?* N
which they blatantly failed to do.- {. \: _; w, \3 C: p# _7 Z
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First, to identify Ye’s performance increase, Ewen Callaway compared her* ~+ l/ G# Z& o2 T: C
Olympic 400-metre IM time with her performance at the World Championships in
1 R; Z$ u* |0 ^3 Q( J2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “) W6 p1 n x( A
anomalous” improvement of around 7 seconds (6.72 s). In fact, her previous
. Q0 F. Z0 D. R: o5 Dpersonal best was 4:33.79 at the Asian Games in 2010. This leads to an
0 e, `& K5 e# }7 ]improvement of 5.38 seconds. In a sporting event in which 0.1 s can be the
) ~; T1 `" V1 Z0 u4 Adifference between the gold and silver medal, I see no reason for 5.38 s to
( J" g( j& h9 p& ?1 ~' G0 Q2 Ebe treated as 7 s." ?( l; ?0 S0 M4 r( p9 ]) [! ^+ x
$ Z: Q3 M8 {# d% M! P) u& rSecond, as previously pointed out, Ye is only 16 years old and her body is* b% X, P1 u; h! y8 ~! V9 E& M
still developing. Bettering oneself by 5 seconds over two years may seem0 K& k$ A$ m; A8 B) P
impossible for an adult swimmer, but it certainly happens among youngsters.
/ X& i/ \5 |! c% s; _: F7 Z$ Q. tAn interview with Australian gold medallist Ian Thorpe revealed that his 400) l) ~1 W" x- u' g& x
-metre freestyle time improved by 5 seconds between the ages of 15 and 16.5 C$ K' }" Q3 P6 ?. @
For regular people, including Callaway, it may be hard to imagine what an: O7 z C( r7 |6 e9 C" j, ^- p
elite swimmer can achieve as he or she matures and undergoes scientific and* g4 z* |- J( Q* ]0 p
persistent training. But jumping to the conclusion that it is “anomalous”
+ Y- T' m$ y! H" v8 F: Ybased on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.- K4 ]4 D1 e' N3 h8 s- g
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Third, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook0 q0 R9 s. w; T3 e/ ^
example of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in' D$ X' G$ r0 j6 ]4 E. Q4 W
the last 50 metres, but Lochte had a huge lead in the first 300 metres, so$ ]( W; ~4 Y1 r2 N
he chose not to push himself too hard and to conserve his energy for later
% s2 r0 `$ t0 c! @, H0 xevents (whether this conforms to the Olympic spirit and the ‘use one’s k. Z! |2 C6 h- z0 ~; _& f& w
best efforts to win a match’ requirement that the Badminton World) Q0 |, A0 S" U
Federation recently invoked to disqualify four badminton pairs is another& G8 f& B. e" z! w8 W' Q$ ?
topic worth discussing, though probably not in Nature). Ye, on the other
- w( P) y v, yhand, was trailing behind after the first 300 metres and relied on freestyle b9 d8 S1 J- r$ p( ?
, in which she has an edge, to win the race. Failing to mention this
3 t5 B9 ~2 {- K0 rstrategic difference, as well as the fact that Lochte is 23.25 seconds5 I5 j0 {# f, _+ I
faster (4:05.18) than Ye overall, creates the illusion that a woman swam
, A" }' O! S! w3 rfaster than the best man in the same sport, which sounds impossible. Putting1 r1 y" k$ d+ n1 S/ e+ n) f! d; b2 \
aside the gender argument, I believe this is still a leading question that3 T3 F! y. w: T
implies to the reader that there is something fishy going on.. H, z" ?" P' Z" N1 @
1 @* Y, q- ?( z* i$ mFourth is another example of cherry-picking. In the same event, there are
8 c; W! s" w! p3 W' x/ s$ sfour male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93
9 U! l# L( r/ ?' J& T" qs) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s3 D5 x8 G, R( i% a* M [: ]
), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns- u% o$ S6 k# l6 [& ^
out, if we are just talking about the last 50 metres in a 400-metre IM,8 l. z7 V' f$ r7 w5 q( b8 Q
Lochter is not the example I would have used if I were the author. What kind# \9 \+ X8 b% Q j0 ^: b
of scientific rigorousness is Callaway trying to demonstrate here? Is it* o7 E1 N; H4 C4 x
logical that if Lochter is the champion, we should assume that he leads in
: S( ?6 K; `" t) }$ v( gevery split? That would be a terrible way to teach the public how science
/ r" K! C% |+ p3 ^$ g$ r' T, jworks.
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Fifth is the issue I oppose the most. Callaway quotes Ross Tucker and0 H8 y9 e+ G/ @1 M. a: \
implies that a drug test cannot rule out the possibility of doping. Is this q8 g) E! ], r6 ^. s
kind of agnosticism what Nature really wants to teach its readers? By that6 b$ L% ^2 Z3 C* u5 t5 w# w" l
standard, I estimate that at least half of the peer-reviewed scientific
5 F; R* s" N; I$ O7 |$ U y7 Lpapers in Nature should be retracted. How can one convince the editors and' F) B6 ~+ |0 {- p+ C5 o: r. k
reviewers that their proposed theory works for every possible case? One
4 ~% \2 F* i) U x3 xcannot. One chooses to apply the theory to typical examples and to
8 ^# H# K& l# Y" S$ X$ l5 _demonstrate that in (hopefully) all scenarios considered, the theory works v: c1 y% M% n) v; p' G* U
to a degree, and that that should warrant publication until a counterexample6 L6 J( s3 J/ Z p
is found. I could imagine that Callaway has a sceptical mind, which is
. e% M; G4 d$ s) ]3 U: B qcrucial to scientific thinking, but that would be put to better use if he
4 W# D& w( M5 |* Z9 Dwrote a peer-reviewed paper that discussed the odds of Ye doping on a highly. y, B! L% t2 y# I0 V" |
advanced, non-detectable drug that the Chinese have come up with in the
4 e+ D9 p S0 B; l1 E! z3 J( Mpast 4 years (they obviously did not have it in Beijing, otherwise why not
, ~5 l- W! r- t5 ^: S, J6 `7 buse it and woo the audience at home?), based on data and rational derivation& O. x z# ?: q
. This article, however, can be interpreted as saying that all athletes are
7 X3 W) x$ r7 o: J, b0 c- i0 ~doping and the authorities are just not good enough to catch them. That may% p3 K, C" s* Z* h- K( V- m" l
be true, logically, but definitely will not make the case if there is ever a1 ^( ]0 Y& m5 t0 g
hearing by the governing body for water sports, FINA, to determine if Ye% |0 b6 V3 n1 G' Q' I# |
has doped. To ask whether it is possible to obtain a false negative in a: m* @% f5 d$ e$ L+ ^0 Z
drug test looks like a rigged question to me. Of course it is possible:
C3 ]+ V. t- p% Dother than the athlete taking a drug that the test is not designed to detect
|- {. g. z' \: V% b8 H, anyone who has taken quantum 101 will tell you that everything is
8 @7 B: z" |; C6 _probabilistic in nature, and so there is a probability that the drug in an
# }" H8 B. v/ N) Z5 Yathlete’s system could tunnel out right at the moment of the test. A slight7 I5 U; N# E5 h" h7 `
chance it may be, but should we disregard all test results because of it?
" U" K! k9 R2 T1 T. f) I) `Let’s be practical and reasonable, and accept that the World Anti-Doping
8 D+ ^, {/ G3 U; gagency (WADA) is competent at its job. Ye’s urine sample will be stored for
9 Y9 k2 W' {( e% ?/ C' b6 Jeight years after the contest for future testing as technology advances.5 k- B6 Z* \3 A9 T8 B0 K: p9 l
Innocent until proven guilty, shouldn’t it be?5 D8 d5 T! g+ H0 ]: s Z
9 o6 d1 J1 @6 b& ^" QSixth, and the last point I would like to make, is that the out-of-
8 W1 F! g. R* Q8 b( M# ocompetition drug test is already in effect, which Callaway failed to mention
4 E: r1 J* |/ j" [3 @. p( b. As noted in the president of WADA’s press release, drug testing for
) m* J- x) V. k/ y3 oOlympians began at least six months before the opening of the London
9 c# k1 v. _5 ]1 @Olympics. Furthermore, 107 athletes have been banned from this Olympics for
& t# a8 N' A X! wdoping. That may be the reason that “everyone will pass at the Olympic
/ p) Z4 b* ^5 l8 p; n% p! ?games. Hardly anyone fails in competition testing” — those who did dope. j) F, \. t. p" B9 |8 a Z9 r
have already been caught and sanctioned. Callaway is free to suggest that a B# g% o9 u$ Y8 N6 O6 m
player could have doped beforehand and fooled the test at the game, but this
6 ?) K% ]. o; ^" Ypossibility is certainly ruled out for Ye.
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4 [7 [0 l; Q, q P! B8 ]Over all, even though Callaway did not falsify any data, he did (
. w9 f7 Z2 J/ R, |# ]$ D( E: }intentionally or not) cherry-pick data that, in my view, are far too0 P/ V# s H L t4 d8 r
suggestive to be fair and unbiased. If you want to cover a story of a t9 G5 \ U& ^3 |& `) [& i" ~
suspected doping from a scientific point of view, be impartial and provide
m2 r8 V* K, R# v/ j, |all the facts for the reader to judge. You are entitled to your
1 U; n3 y) S* iinterpretation of the facts, and the expression thereof in your piece,/ W- n ^0 Y) @ y' b; @
explicitly or otherwise, but showing only evidence that favours your
% n" ~/ i1 D8 Y/ ]1 H' largument is hardly good science or journalism. Such an article in a journal3 h4 H0 F5 c& w6 L& w v( l ~
such as Nature is not an appropriate example of how scientific research or
' v0 Q# T5 a$ \3 c% {9 Sreporting should be done. |
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